Doctor-patient Communication is an important tool in health care by which physicians and patients relate to each other and attempt to achieve therapeutic goals (Hulsman, et al. 1999). Numerous studies have already been carried out to investigate the nature of such Communication and ways of enhancing its quality (e.g. Cassell, 1985 and Chan, et al. 2002). However, review of the literature indicates that medical education on doctor-patient Communication has not made any comparison between the patients' perceptions of general practitioners (GPs) and those of specialist physicians (SPs). The aims of the current study are therefore to investigate and compare patients' Satisfaction with regard to clinic interactions they have with GPs on the one hand and SPs on the other. This is done by the use of a IS-item questionnaire, developed based on the key principles of doctor-patient Communication, suggested by psycho-socialists and clinical psychologists (e.g. Kaplan and Sadock 1998). The questionnaire was completed by a total of 1209 subjects, 485 of whom were GPs' patients and 724 who had referred to SPs. According to the results, Satisfaction rate with GPs was significantly greater than that with SPs (i.e. 54% vs. 48%, p= 0.04). In other words, patients referring to GPs were significantly more satisfied with their clinic interviews than those referring to SPs.